Enduring Changes in Brain and Behavior Produced by Chronic Amphetamine Administration: A Review and Evaluation of Anima1 Models of Amphetamine Psychosis
نویسنده
چکیده
5. Introduction ............................................................................................................................................. The effects of continuous amphetamine administration on brain and behavior (amphetamine neurotoxicity) ..................... The behavioral consequences of repeated intermittent amphetamine administration (behavioral sensitization) ................. 3.1. The major characteristics of behavioral sensitization .................................................................................... 3.1.1. Behavior .................................................................................................................................. 3.1.2. Injection paradigm ..................................................................................................................... 3.1.3. Sex differences ........................................................................................................................... 3.1.4. Summary ..................................................................................................................................
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Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis.
Some people who repeatedly use stimulant drugs, such as amphetamine (AMPH), develop an AMPH-induced psychosis that is similar to paranoid schizophrenia. There has been, therefore, considerable interest in characterizing the effects of chronic stimulant drug treatment on brain and behavior in non-human animals, and in developing an animal model of AMPH psychosis. A review of this literature show...
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